SCHEMBL31344706

SCHEMBL31344706

CC[S@@+]([O-])c1cc(OC(C)(C)C#N)cnc1/C(N)=N/OS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 2/20 0.33
HTT P42858 1/20 0.33
F2 P00734 3/20 0.32
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
KDM4E B2RXH2 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
AHR P35869 1/20 0.30
PKM P14618 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31344778 0.83 MAPT (0.48) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL31344759 0.82 MAPT (0.46) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL31344768 0.82 MAPT (0.42) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL31344708 0.78 NPSR1 (0.40)
SCHEMBL31344684 0.77 ALDH1A1 (0.32) MAPTALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL31344775 0.72 KDM4E (0.42) MAPTALDH1A1SMN1; SMN2HTTKDM4E
SCHEMBL31344694 0.71 ALDH1A1 (0.31) MAPTALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL31344773 0.70 KDM4E (0.40) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL31344695 0.66
SCHEMBL31267240 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724447-A1 SYNTHESIS OF CYCLIC ACYL SULFOXIMINES Syngenta Crop Protection AG (CH) 2026-04-15 EP disclosed
WO-2024252006-A1 SYNTHESIS OF CYCLIC ACYL SULFOXIMINES SYNGENTA CROP PROTECTION AG (CH) 2024-12-12 WO disclosed