Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31603443 | 0.86 | MAPT (0.56) | MAPTKMT2AGAAWDR5ALDH1A1 | |
| SCHEMBL6260473 | 0.80 | NPC1 (0.70) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL26758054 | 0.79 | KDM4E (0.48) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11361118 | 0.77 | KCNMA1 (0.72) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL7301422 | 0.75 | HTT (0.73) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL31499394 | 0.74 | NPC1 (0.69) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL24380012 | 0.74 | KCNMA1 (0.81) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL22007919 | 0.74 | KMT2A (0.65) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL31407773 | 0.74 | NPC1 (0.60) | MAPTKCNMA1NPC1RAB9AKMT2A | |
| SCHEMBL2131627 | 0.73 | CXCR1 (0.62) | MAPTKCNMA1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569651-A | Carboxamide derivatives, pharmaceutical compositions containing the same, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-03-07 | — | — | CN | disclosed |