Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21319823 | 1.00 | KRAS (0.45) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL21319909 | 0.91 | KRAS (0.43) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL31344938 | 0.91 | KRAS (0.43) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL19636820 | 0.91 | KRAS (0.43) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL21315045 | 0.90 | KRAS (0.46) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL29239725 | 0.87 | KRAS (0.43) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL19637243 | 0.87 | KRAS (0.39) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL21315048 | 0.86 | KRAS (0.45) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL19959303 | 0.85 | KRAS (0.39) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL29493406 | 0.85 | KRAS (0.39) | KRASSOS1VHLCDK7CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4501932-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| EP-3880208-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-11-20 | — | — | EP | disclosed |