Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TTPA | P49638 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721090 | 0.83 | PTGS1 (0.63) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| Apc-100 SCHEMBL3134545 | 0.79 | CYP3A4 (0.60) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL12434165 | 0.78 | PTGS1 (0.40) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8199223 | 0.77 | PSEN1 (0.45) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8259133 | 0.75 | PTGS1 (0.45) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL10074171 | 0.74 | PSEN1 (0.60) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL20032244 | 0.74 | PSEN1 (0.48) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL13072776 | 0.73 | PSEN1 (0.51) | GSTO1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL18785106 | 0.73 | GSTO1 (1.00) | GSTO1PSEN1ALOX5MEN1KMT2A | |
| SCHEMBL2507605 | 0.73 | GSTO1 (1.00) | GSTO1PSEN1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703417-B2 | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-8329401-B2 | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120283141-A1 | ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED DETECTION OF ANALYTES OF INTEREST | VENTANA MEDICAL SYSTEMS, INC. | 2012-11-08 | — | — | US | disclosed |
| US-20100105566-A1 | Enzyme-Catalyzed Metal Deposition for the Enhanced Detection of Analytes of Interest | VENTANA MEDICAL SYSTEMS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-7642064-B2 | Binding enzyme-labeled conjugate (antibodies, haptens with phospatases, galactosidases, beta-glucosidases, esterases, and beta-lactamases) to epitope/sequence in presence of redox-inactive reductive species and soluble gold/silver ion; solid phase synthesis; kits | VENTANA MEDICAL SYSTEMS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7632652-B2 | Binding enzyme-labeled conjugate (antibodies, haptens with phospatases, galactosidases, beta-glucosidases, esterases, and beta-lactamases) to epitope/sequence in presence of redox-inactive reductive species and soluble gold/silver ion; kits | VENTANA MEDICAL SYSTEMS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1636586-B1 | ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES | VENTANA MED SYST INC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1636586-A2 | ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2006-03-22 | — | — | EP | disclosed |
| US-20050100976-A1 | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest | VENTANA MEDICAL SYSTEMS, INC. | 2005-05-12 | — | — | US | disclosed |
| WO-2005003777-A2 | ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20040265922-A1 | Enzyme-catalyzed metal deposition for the enhanced in situ detection of immunohistochemical epitopes and nucleic acid sequences | VENTANA MEDICAL SYSTEMS, INC. | 2004-12-30 | — | — | US | disclosed |