Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26617970 | 1.00 | KDM4E (0.56) | KDM4ENR4A2TP53PLA2G2APDE3B | |
| SCHEMBL26617774 | 0.87 | KDM4E (0.57) | KDM4ENR4A2TP53PLA2G2APDE3B | |
| SCHEMBL21449438 | 0.85 | CCR6 (0.46) | KDM4ETSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL16234345 | 0.77 | KDM4E (0.51) | KDM4EMEN1KMT2ATSHRRXFP1 | |
| SCHEMBL24650616 | 0.77 | MPL (0.49) | KDM4ENR4A2MEN1KMT2ATSHR | |
| SCHEMBL17824436 | 0.76 | KDM4E (0.48) | KDM4ETP53PDE3BPDE3AMEN1 | |
| SCHEMBL8643551 | 0.76 | RXFP1 (0.52) | KDM4ENR4A2NQO2RXFP1 | |
| SCHEMBL6706992 | 0.74 | PDE3B (0.46) | KDM4EPDE3BPDE3AMEN1KMT2A | |
| SCHEMBL17824528 | 0.74 | MAPT (0.47) | KDM4ETP53PLA2G2APDE3BPDE3A | |
| SCHEMBL21705316 | 0.73 | PDE3B (0.43) | KDM4ETP53PDE3BPDE3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585247-A | Bicyclic heterocyclic amide inhibitors of nav1.8 for the treatment of pain | 赛特温治疗公司 | 2025-03-07 | — | — | CN | disclosed |