Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404380 | 0.83 | PSMB8 (0.41) | PDE3BPDE3ANQO2CYP1A2MAOA | |
| SCHEMBL21449661 | 0.79 | BACE1 (0.41) | PDE3BPDE3ANQO2CYP1A2CYP2A6 | |
| SCHEMBL2284036 | 0.75 | ALDH1A1 (0.53) | NQO2KDM4EALDH1A1GLAKMT2A | |
| SCHEMBL30685964 | 0.75 | ALDH1A1 (0.53) | NQO2KDM4EALDH1A1GLAKMT2A | |
| SCHEMBL26617970 | 0.74 | KDM4E (0.56) | PDE3BPDE3ANQO2KDM4EALDH1A1 | |
| SCHEMBL31345618 | 0.74 | KDM4E (0.56) | PDE3BPDE3ANQO2KDM4EALDH1A1 | |
| SCHEMBL4160733 | 0.73 | ALDH1A1 (0.60) | PDE3BPDE3ANQO2CYP1A2CYP2A6 | |
| SCHEMBL7045373 | 0.73 | CYP1A2 (0.42) | PDE3BPDE3ANQO2CYP1A2CYP2A6 | |
| SCHEMBL30914218 | 0.73 | MAOA (0.45) | CYP1A2CYP2A6MAOAMAOBKDM4E | |
| SCHEMBL28475918 | 0.73 | MAOA (0.45) | CYP1A2CYP2A6MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044217-A1 | Process to produce halo-4-phenoxyquinolines | KRUMEL KARL LEOPOLD (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044217-A1 | Process to produce halo-4-phenoxyquinolines | KCNQ4, CYP4X1, KCNQ2 | PDE3B 1922/4885PDE3A 3084/4885NQO2 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.