SCHEMBL31345636

SCHEMBL31345636

O=C(O)c1cc2ccncc2nc1N1CCCC(F)(F)CC1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SCN10A Q9Y5Y9 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26617707 1.00 SCN10A (0.42) SCN10A
SCHEMBL26617474 0.91 SCN10A (0.42) SCN10A
SCHEMBL31345642 0.91 SCN10A (0.42) SCN10A
SCHEMBL26617769 0.85 ALDH1A1 (0.46) SCN10A
SCHEMBL30681905 0.85 MEN1 (0.44) SCN10A
SCHEMBL26617818 0.85 MEN1 (0.44) SCN10A
SCHEMBL26617697 0.83 SCN10A (0.40) SCN10A
SCHEMBL26617572 0.82 SCN10A (0.44) SCN10A
SCHEMBL26617837 0.81 SCN10A (0.40) SCN10A
SCHEMBL26617935 0.81 SCN10A (0.39) SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119585247-A Bicyclic heterocyclic amide inhibitors of nav1.8 for the treatment of pain 赛特温治疗公司 2025-03-07 — — CN disclosed
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