SCHEMBL31345792

SCHEMBL31345792

O=C(O)[C@H](Cc1ccccc1)N[18F]

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.57
MMP2 P08253 4/20 0.57
MMP9 P14780 3/20 0.57
ADAMTS4 O75173 1/20 0.57
NPSR1 Q6W5P4 1/20 0.56
CYP1A2 P05177 1/20 0.55
NAALAD2 Q9Y3Q0 2/20 0.54
FOLH1 Q04609 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ACE P12821 1/20 0.53
ALDH1A1 P00352 1/20 0.53
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144009 1.00 MME (0.57) MMEMMP2MMP9ADAMTS4NPSR1
SCHEMBL199980 1.00 MME (0.57) MMEMMP2MMP9ADAMTS4NPSR1
SCHEMBL144008 1.00 MME (0.57) MMEMMP2MMP9ADAMTS4NPSR1
Trifluoroacetic Acid SCHEMBL31261334 0.93 ACE (0.55) MMEMMP2MMP9ADAMTS4NPSR1
SCHEMBL8501294 0.86 NAALAD2 (0.47) MMEMMP2MMP9ADAMTS4NPSR1
SCHEMBL1008925 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1ACE
SCHEMBL22290826 0.85 ALDH1A1 (0.57) MMEFOLH1ACEALDH1A1
SCHEMBL29964738 0.85 ALDH1A1 (0.57) MMEFOLH1ACEALDH1A1
SCHEMBL1008926 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1ACE
SCHEMBL15833929 0.85 EPHX1 (0.53) MMENPSR1CYP1A2ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383827-A1 DIFLUOROCARBENE RADIOSYNTHESIS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383827-A1 DIFLUOROCARBENE RADIOSYNTHESIS RFC2, FDFT1, AFF1 MME 2777/4885MMP2 3868/4885MMP9 4152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.