Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158409 | 0.91 | NPY1R (0.36) | NPY1RSLC6A12 | |
| SCHEMBL2158340 | 0.90 | SMN1; SMN2 (0.40) | MAPTTP53HTTNPC1RAB9A | |
| SCHEMBL12395525 | 0.83 | SMN1; SMN2 (0.39) | HTTNPC1RAB9A | |
| SCHEMBL2157463 | 0.82 | SMN1; SMN2 (0.41) | NPC1RAB9A | |
| SCHEMBL2158000 | 0.81 | EPHX2 (0.36) | NPY1RSLC6A12 | |
| SCHEMBL2157606 | 0.79 | MAPT (0.46) | MAPTTP53KDM4EHTTATM | |
| SCHEMBL2157539 | 0.79 | CHRM1 (0.43) | CHRM3 | |
| SCHEMBL3811676 | 0.78 | SLC6A12 (0.35) | NPC1RAB9ANPY1RSLC6A12 | |
| SCHEMBL2158394 | 0.77 | MEN1 (0.52) | MAPTTP53KDM4EHTTATM | |
| SCHEMBL318365 | 0.77 | KDM4E (0.40) | MAPTTP53KDM4EHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206709-A2 | Thiophene derivatives as antiviral agents for flavivirus infection | Virochem Pharma Inc. (CA) | 2010-07-14 | — | — | EP | disclosed |