SCHEMBL3134591

SCHEMBL3134591

C=CCN1C(=O)SC(=Cc2ccc(-c3ccccc3)o2)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
POLB P06746 4/20 0.63
ITGB2 P05107 3/20 0.62
ITGAM P11215 3/20 0.62
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MAPK1 P28482 1/20 0.56
RAB9A P51151 2/20 0.56
ENPP2 Q13822 1/20 0.53
PIK3CG P48736 1/20 0.51
PTPN22 Q9Y2R2 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
NPC1 O15118 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
EP300 Q09472 1/20 0.48
CREBBP Q92793 1/20 0.48
STAT3 P40763 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134585 1.00 MEN1 (0.63) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL3134579 1.00 MEN1 (0.63) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL12177201 0.88 KMT2A (0.64) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL12177595 0.88 KMT2A (0.64) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL3126564 0.88 POLB (0.80) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL3135468 0.88 POLB (0.58) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL3126558 0.88 POLB (0.80) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL3135474 0.88 POLB (0.58) MEN1KMT2APOLBITGB2ITGAM
SCHEMBL3126561 0.88 POLB (0.80) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL3135461 0.88 POLB (0.58) MEN1KMT2APOLBITGB2ITGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120219613-A1 Novel Antiviral Agents for Enveloped Viruses THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-08-30 US disclosed
WO-2010044924-A1 NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120219613-A1 Novel Antiviral Agents for Enveloped Viruses MAVS, LAMP1, HAVCR2 MEN1 4512/4885KMT2A 2561/4885POLB 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.