SCHEMBL31345992

SCHEMBL31345992

Oc1cc(-c2cccc(C3Cc4cc(C(F)(F)F)ccc4O3)c2)on1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.39
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
TEAD1 P28347 1/20 0.35
CYP19A1 P11511 1/20 0.34
CASP3 P42574 1/20 0.34
CASP7 P55210 1/20 0.34
CASP8 Q14790 1/20 0.34
TRPV1 Q8NER1 1/20 0.33
EPHX2 P34913 1/20 0.33
AR P10275 1/20 0.33
HTR1A P08908 1/20 0.32
S1PR1 P21453 1/20 0.32
CFTR P13569 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346072 0.80 FFAR1 (0.40) FFAR1TEAD1CYP19A1ARHTR1A
SCHEMBL31346059 0.78 FFAR1 (0.38) FFAR1CYP19A1HTR1A
SCHEMBL31346041 0.78 FFAR1 (0.38) FFAR1CYP19A1HTR1A
SCHEMBL31345962 0.77 KDM1A (0.40) FFAR1TEAD1CASP3CASP7CASP8
SCHEMBL31345981 0.77 KDM1A (0.40) FFAR1TEAD1CASP3CASP7CASP8
SCHEMBL31345965 0.75 FFAR1 (0.37) FFAR1TEAD1CYP19A1CASP3CASP7
SCHEMBL31346068 0.75 MRGPRX4 (0.45) FFAR1TEAD1CASP3CASP7CASP8
SCHEMBL31345963 0.75 TEAD1 (0.42) FFAR1TEAD1CYP19A1ARHTR1A
SCHEMBL31346002 0.75 TEAD1 (0.42) FFAR1TEAD1CYP19A1ARHTR1A
SCHEMBL31345978 0.73 CFTR (0.49) FFAR1ARCFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed