Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25957732 | 0.95 | GPR119 (0.50) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL25339536 | 0.95 | GPR119 (0.52) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL25958866 | 0.95 | GPR119 (0.52) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL31599049 | 0.95 | GPR119 (0.52) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL31291130 | 0.94 | GPR119 (0.49) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL31291137 | 0.94 | GPR119 (0.49) | GPR119JAK2JAK1USP30DPP4 | |
| SCHEMBL22750432 | 0.93 | GPR119 (0.59) | GPR119JAK2JAK1USP30STS | |
| SCHEMBL22750429 | 0.93 | GPR119 (0.59) | GPR119JAK2JAK1USP30STS | |
| SCHEMBL22750434 | 0.93 | GPR119 (0.59) | GPR119JAK2JAK1USP30STS | |
| SCHEMBL23751448 | 0.93 | GPR119 (0.59) | GPR119JAK2JAK1USP30STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746968-A1 | PYRROLIDINE COMPOUNDS LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024216-A1 | PYRROLIDINE COMPOUNDS Lp(a) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |