Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29449194 | 0.80 | KDM4E (0.57) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL18033083 | 0.75 | KDM4E (0.56) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL12395170 | 0.74 | KDM4E (0.55) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL12395173 | 0.74 | KDM4E (0.55) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL18033166 | 0.72 | KDM4E (0.52) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29683890 | 0.71 | MAPT (0.83) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL18118625 | 0.70 | MEN1 (0.79) | GAAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL15180305 | 0.68 | KDM4E (0.57) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31673809 | 0.67 | LMNA (0.73) | GAAKDM4EMAPTMEN1TSHR | |
| SCHEMBL15101603 | 0.67 | LMNA (0.73) | GAAKDM4EMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |