Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347185 | 0.85 | CDK2 (0.41) | CDK2KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL31347166 | 0.78 | MEN1 (0.40) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8872534 | 0.77 | NAMPT (0.43) | KMT2AMEN1TDP1GSK3BMAPT | |
| SCHEMBL31347295 | 0.76 | CHRM4 (0.43) | CDK2KMT2ACYP1A2CHRM4CYP3A4 | |
| SCHEMBL26107366 | 0.73 | KMT2A (0.52) | CDK2KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL17767940 | 0.71 | GRIN2D (0.41) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL27942973 | 0.71 | GRIN2D (0.41) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL31539799 | 0.71 | GRIN2D (0.41) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL12791626 | 0.69 | CDK2 (0.56) | CDK2KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL27413443 | 0.69 | KMT2A (0.54) | CDK2KMT2AMEN1GABBR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |