Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16831824 | 0.80 | MAPT (0.39) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31347217 | 0.79 | GRIN2D (0.40) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17767940 | 0.79 | GRIN2D (0.41) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31539799 | 0.79 | GRIN2D (0.41) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27942973 | 0.79 | GRIN2D (0.41) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31347124 | 0.78 | CDK2 (0.54) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8873854 | 0.77 | L3MBTL1 (0.45) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8872534 | 0.77 | NAMPT (0.43) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31347185 | 0.77 | CDK2 (0.41) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8873582 | 0.76 | POLB (0.45) | MEN1KMT2AMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |