Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 8/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104506 | 1.00 | KDM4E (0.46) | KDM4ENQO2NR4A2SMN1; SMN2ABL1 | |
| SCHEMBL16341884 | 0.77 | KDM4E (0.46) | KDM4ENQO2SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL21610985 | 0.73 | CHEK1 (0.46) | MAP2K1CHEK1 | |
| SCHEMBL14816677 | 0.72 | KDM4E (0.47) | KDM4ENQO2SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL31347077 | 0.71 | KDM4E (0.58) | KDM4ENR4A2SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL2158555 | 0.71 | KDM4E (0.58) | KDM4ENR4A2SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL17979068 | 0.70 | KDM4E (0.50) | KDM4ENQO2SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL29644283 | 0.69 | MAP2K1 (0.57) | KDM4ENR4A2MAP2K1 | |
| SCHEMBL26979129 | 0.69 | MAP2K1 (0.57) | KDM4ENR4A2MAP2K1 | |
| SCHEMBL16476635 | 0.69 | KDM4E (0.43) | KDM4ENQO2SMN1; SMN2ABL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |