Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693205 | 1.00 | RXFP1 (0.53) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL11932852 | 0.86 | RXFP1 (0.53) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL12596677 | 0.85 | RXFP1 (0.56) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL30521190 | 0.85 | RXFP1 (0.56) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL1601224 | 0.83 | RXFP1 (0.58) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL10472153 | 0.81 | HDAC1 (0.47) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL15594102 | 0.81 | ALDH1A1 (0.50) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL15594109 | 0.79 | ALDH1A1 (0.45) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL13715560 | 0.79 | CA1 (0.44) | RXFP1CA1CA2CA9HDAC1 | |
| SCHEMBL2429572 | 0.79 | RXFP1 (0.53) | RXFP1CA1CA2CA9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365682-B2 | Process to make GLP1 RA and intermediates therefor | ELI LILLY AND COMPANY (US) | 2025-07-22 | — | — | US | disclosed |
| US-20250042899-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365682-B2 | Process to make GLP1 RA and intermediates therefor | GLP1R, GIPR, NPY4R | RXFP1 7/4885CA1 2056/4885CA2 2493/4885 |
| US-20250042899-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | GLP1R, GIPR, NPY4R | RXFP1 7/4885CA1 2056/4885CA2 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.