Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.59 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348008 | 1.00 | NPC1 (0.74) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL11266749 | 0.88 | NPC1 (0.78) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL20377223 | 0.87 | RAB9A (0.76) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL1355332 | 0.87 | NPC1 (0.76) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL31365954 | 0.85 | NPC1 (0.74) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL31365955 | 0.85 | NPC1 (0.74) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL31365952 | 0.85 | RAB9A (1.00) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL31365958 | 0.85 | NPC1 (0.74) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL1355373 | 0.82 | RAB9A (0.69) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 | |
| SCHEMBL1353266 | 0.82 | NPC1 (0.69) | NPC1RAB9AADORA2AEPHB3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655626-B | Cyclopropanamide compound containing imidazo [ l,2-a ] pyridine skeleton and preparation method and application thereof | 遵义医科大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-117105936-B | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2025-01-24 | — | — | CN | disclosed |