Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.58 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662044 | 1.00 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31348400 | 0.92 | KRAS (0.60) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30702897 | 0.92 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31662384 | 0.91 | KRAS (0.48) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30702938 | 0.91 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31323342 | 0.90 | KRAS (0.68) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27243298 | 0.90 | KRAS (0.68) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30810145 | 0.89 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27243469 | 0.89 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30779000 | 0.88 | KRAS (0.59) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735439-A1 | KRAS INHIBITORS | Bristol-Myers Squibb Company (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006967-A1 | KRAS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-01-02 | — | — | WO | disclosed |