Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142335 | 0.95 | S1PR1 (0.45) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3128858 | 0.92 | S1PR1 (0.45) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3134876 | 0.91 | S1PR1 (0.55) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3137400 | 0.89 | S1PR1 (0.53) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3132696 | 0.87 | S1PR1 (0.46) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3137704 | 0.86 | S1PR1 (0.55) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3135528 | 0.82 | S1PR1 (0.57) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3128850 | 0.82 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3141824 | 0.82 | S1PR1 (0.48) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3135253 | 0.80 | S1PR1 (0.55) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873153-B1 | 3-AZETIDINECARBOXYLIC ACID DERIVATIVES FOR USE AS IMMUNOSUPPRESSANTS | DAIICHI SANKYO CO LTD (JP) | 2010-07-07 | — | — | EP | claimed |