SCHEMBL31348922

SCHEMBL31348922

CCc1cncnc1N1CCN(Cc2nc3ccc(C(F)(F)F)cc3[nH]2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 1.00
GRM2 Q14416 1/20 0.44
LMNA P02545 1/20 0.44
DRD4 P21917 2/20 0.43
PIK3CD O00329 1/20 0.43
PIK3CB P42338 1/20 0.43
SLC2A1 P11166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964170 1.00 RPS6KB1 (1.00) RPS6KB1GRM2LMNADRD4PIK3CD
SCHEMBL30041857 0.93 RPS6KB1 (0.86) RPS6KB1GRM2LMNADRD4
SCHEMBL17714406 0.93 RPS6KB1 (0.86) RPS6KB1GRM2LMNADRD4
SCHEMBL30040497 0.86 RPS6KB1 (0.75) RPS6KB1GRM2LMNADRD4
SCHEMBL23932538 0.86 RPS6KB1 (0.75) RPS6KB1GRM2LMNADRD4
SCHEMBL23964274 0.82 RPS6KB1 (0.69) RPS6KB1GRM2LMNADRD4PIK3CD
SCHEMBL30042095 0.82 RPS6KB1 (0.69) RPS6KB1GRM2LMNADRD4PIK3CD
SCHEMBL23932512 0.81 RPS6KB1 (0.68) RPS6KB1GRM2LMNADRD4
SCHEMBL23932547 0.80 RPS6KB1 (0.66) RPS6KB1DRD4PIK3CDPIK3CBSLC2A1
SCHEMBL25186830 0.79 RPS6KB1 (0.65) RPS6KB1LMNADRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119112898-A Medicine for treating Alzheimer disease learning and memory disorder and application thereof 徐州医科大学 2024-12-13 CN disclosed