SCHEMBL25186830

SCHEMBL25186830

CCc1cncnc1N1CCN(Cc2nc3ccc(COCCOC)cc3[nH]2)CC1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 0.65
PARP1 P09874 5/20 0.41
DRD4 P21917 9/20 0.39
TBK1 Q9UHD2 1/20 0.38
PARP6 Q2NL67 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
PARP3 Q9Y6F1 1/20 0.38
DRD2 P14416 1/20 0.38
F10 P00742 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37
MLLT1 Q03111 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932512 0.87 RPS6KB1 (0.68) RPS6KB1PARP1DRD4DRD2MLLT1
SCHEMBL23932576 0.86 RPS6KB1 (0.47) RPS6KB1PARP1DRD4PARP2DRD2
SCHEMBL30041918 0.86 RPS6KB1 (0.47) RPS6KB1PARP1DRD4PARP2DRD2
SCHEMBL30040497 0.81 RPS6KB1 (0.75) RPS6KB1PARP1DRD4DRD2F10
SCHEMBL23932538 0.81 RPS6KB1 (0.75) RPS6KB1PARP1DRD4DRD2F10
SCHEMBL31348922 0.79 RPS6KB1 (1.00) RPS6KB1DRD4LMNA
SCHEMBL23964170 0.79 RPS6KB1 (1.00) RPS6KB1DRD4LMNA
SCHEMBL30041176 0.78 RPS6KB1 (0.40) RPS6KB1PARP1DRD4DRD2HTT
SCHEMBL23932573 0.78 KMT2A (0.43) DRD2
SCHEMBL30041288 0.78 KMT2A (0.43) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 RPS6KB1 316/4885PARP1 193/4885DRD4 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.