SCHEMBL31348952

SCHEMBL31348952

CC[C@H](C)[C@H](N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)C(=O)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.46
FKBP1A P62942 5/20 0.46
ACE P12821 3/20 0.45
FAP Q12884 2/20 0.44
TSHR P16473 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483482 0.86 PREP (0.47) PREPFKBP1AACEFAPTSHR
SCHEMBL30051887 0.79 DPP4 (0.46) PREPACEFAPDPP8
SCHEMBL30187740 0.77 FKBP1A (0.54) PREPFKBP1AACEKMT2ADPP8
SCHEMBL15371266 0.76 DPP8 (0.57) FKBP1AACEFAPDPP8
SCHEMBL8110892 0.76 DPP8 (0.57) FKBP1AACEFAPDPP8
SCHEMBL10402287 0.76 DPP8 (0.57) FKBP1AACEFAPDPP8
SCHEMBL8365050 0.76 DPP8 (0.57) FKBP1AACEFAPDPP8
Hydrochloric Acid SCHEMBL9034318 0.75 DPP8 (0.56) FKBP1AACEFAPDPP8
Hydrochloric Acid SCHEMBL9034326 0.75 DPP8 (0.56) FKBP1AACEFAPDPP8
Hydrochloric Acid SCHEMBL27869985 0.75 DPP8 (0.56) FKBP1AACEFAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604313-A IL-2 pre-cytokine antibody fusion proteins 普罗维瓦疗法香港有限公司 2025-03-11 CN disclosed
CN-119591725-A IL-2 compositions and methods of use thereof 普罗维瓦疗法香港有限公司 2025-03-11 CN disclosed
CN-112512559-B Compositions and methods for treating NRP 2-related diseases ATYR 医药公司 2025-02-28 CN disclosed