SCHEMBL31349145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23697146	0.88	PDK2 (0.38)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL23697275	0.86	ESR1 (0.35)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL22151603	0.84	PDK2 (0.38)	PDK2MAPTSTK10SLK
	SCHEMBL24883062	0.83	MEN1 (0.37)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL20346073	0.83	PDK2 (0.41)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL20871523	0.82	PDK2 (0.46)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL31011948	0.82	PDK2 (0.46)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL20871524	0.82	MAPT (0.41)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL22182353	0.82	PDK2 (0.35)	PDK2ESR1ESR2MEN1KMT2A
	SCHEMBL22182349	0.82	PDK2 (0.38)	PDK2MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.