Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.38 |
| ▸ | STK10 | O94804 | 2/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969171 | 0.90 | PDK2 (0.38) | PDK2STK10SLKPGRAPP | |
| SCHEMBL23765166 | 0.87 | STK10 (0.39) | PDK2STK10SLKPGRALDH1A1 | |
| SCHEMBL26983129 | 0.87 | ALDH1A1 (0.45) | PDK2ALDH1A1ALOX12MAPK1HSD17B10 | |
| SCHEMBL30691830 | 0.87 | ALDH1A1 (0.45) | PDK2ALDH1A1ALOX12MAPK1HSD17B10 | |
| SCHEMBL30691834 | 0.87 | ALDH1A1 (0.45) | PDK2ALDH1A1ALOX12MAPK1HSD17B10 | |
| SCHEMBL30693237 | 0.86 | KDM1A (0.31) | PDK2PGRTP53MAPT | |
| SCHEMBL24969648 | 0.85 | PDK2 (0.43) | PDK2STK10SLKPGRAPP | |
| SCHEMBL31349145 | 0.84 | PDK2 (0.34) | PDK2STK10SLKMAPT | |
| SCHEMBL29783348 | 0.83 | CAMK1D (0.30) | PTGER4 | |
| SCHEMBL28418620 | 0.83 | PDK2 (0.44) | PDK2STK10SLKPGRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127145-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |