Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MITF | O75030 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349251 | 0.84 | POLB (0.60) | POLBMAPTLMNAL3MBTL1 | |
| SCHEMBL13479639 | 0.83 | POLB (0.60) | POLBL3MBTL1GAA | |
| SCHEMBL31349272 | 0.81 | POLB (0.57) | POLBMAPTLMNAL3MBTL1 | |
| SCHEMBL31349263 | 0.79 | POLB (0.55) | POLBKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13219630 | 0.77 | POLB (0.74) | POLBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL31349290 | 0.77 | POLB (0.60) | POLBL3MBTL1 | |
| SCHEMBL31349298 | 0.77 | POLB (0.57) | POLBKMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL31349258 | 0.77 | POLB (0.57) | POLBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL31349291 | 0.77 | POLB (0.57) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL13219627 | 0.76 | POLB (0.70) | POLBMAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |