Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349306 | 0.87 | POLB (0.51) | POLBSLC2A1L3MBTL1LMNAMAPT | |
| SCHEMBL31349251 | 0.86 | POLB (0.60) | POLBSLC2A1L3MBTL1LMNAMAPT | |
| SCHEMBL13479639 | 0.86 | POLB (0.60) | POLBL3MBTL1 | |
| SCHEMBL31349290 | 0.81 | POLB (0.60) | POLBSLC2A1L3MBTL1 | |
| SCHEMBL31349269 | 0.81 | POLB (0.60) | POLBSLC2A1L3MBTL1 | |
| SCHEMBL31349213 | 0.81 | POLB (0.60) | POLBDRD4DRD5L3MBTL1MAPT | |
| SCHEMBL13219627 | 0.81 | POLB (0.70) | POLBDRD4SLC2A1L3MBTL1LMNA | |
| SCHEMBL31349218 | 0.81 | POLB (0.63) | POLBL3MBTL1LMNAMAPT | |
| SCHEMBL31349226 | 0.80 | POLB (0.58) | POLBSLC2A1L3MBTL1LMNAMAPT | |
| SCHEMBL31349225 | 0.80 | POLB (0.58) | POLBSLC2A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |