Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349227 | 0.90 | POLB (0.56) | POLBKDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL31349219 | 0.86 | POLB (0.57) | POLBL3MBTL1 | |
| SCHEMBL13479639 | 0.84 | POLB (0.60) | POLBL3MBTL1 | |
| SCHEMBL31349226 | 0.83 | POLB (0.58) | POLBKDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL31349236 | 0.83 | POLB (0.53) | POLBL3MBTL1MEN1NPC1KMT2A | |
| SCHEMBL13219627 | 0.82 | POLB (0.70) | POLBKDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL31349298 | 0.82 | POLB (0.57) | POLBL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL31349291 | 0.82 | POLB (0.57) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31349306 | 0.81 | POLB (0.51) | POLBL3MBTL1MAPTLMNATP53 | |
| SCHEMBL11622596 | 0.81 | KDM4E (0.59) | POLBKDM4EALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |