Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349245 | 0.90 | POLB (0.55) | POLBL3MBTL1KDM4EMEN1NPC1 | |
| SCHEMBL31349219 | 0.89 | POLB (0.57) | POLBL3MBTL1SLC2A1 | |
| SCHEMBL31349236 | 0.85 | POLB (0.53) | POLBL3MBTL1MEN1NPC1KMT2A | |
| SCHEMBL31349251 | 0.83 | POLB (0.60) | POLBL3MBTL1MAPTSLC2A1 | |
| SCHEMBL31349291 | 0.82 | POLB (0.57) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31349298 | 0.82 | POLB (0.57) | POLBL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL31349222 | 0.82 | POLB (0.54) | POLBL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31349306 | 0.81 | POLB (0.51) | POLBL3MBTL1MAPTSLC2A1 | |
| SCHEMBL31349213 | 0.81 | POLB (0.60) | POLBL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL13219627 | 0.80 | POLB (0.70) | POLBL3MBTL1KDM4EMAPTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |