Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349447 | 0.81 | USP30 (0.42) | — | |
| SCHEMBL31349589 | 0.80 | MAP3K12 (0.36) | MAP3K12JAK1CCNE1CDK2 | |
| SCHEMBL31349450 | 0.80 | ABL1 (0.36) | — | |
| SCHEMBL31349584 | 0.79 | MAP3K12 (0.36) | MAP3K12JAK1CCNE1CDK2 | |
| SCHEMBL31698989 | 0.73 | AAK1 (0.32) | — | |
| SCHEMBL31349525 | 0.71 | — | — | |
| SCHEMBL17048230 | 0.70 | AURKA (0.36) | JAK1 | |
| SCHEMBL25315851 | 0.70 | AR (0.34) | — | |
| SCHEMBL30506750 | 0.70 | AR (0.34) | — | |
| SCHEMBL26023698 | 0.70 | AR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743078-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015104-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |