Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 11/20 | 0.38 |
| ▸ | HTR2C | P28335 | 9/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 6/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350143 | 0.92 | ADORA3 (0.38) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL31350094 | 0.87 | HRH2 (0.34) | HRH2HTR5AADORA3ADORA1 | |
| SCHEMBL31350206 | 0.87 | HRH2 (0.57) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL31350157 | 0.86 | HRH2 (0.56) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL29360010 | 0.85 | ADORA3 (0.55) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL13140717 | 0.85 | HRH2 (0.44) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL12269794 | 0.81 | HTR2B (0.55) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL19415065 | 0.81 | HTR2B (0.55) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL31350227 | 0.80 | HTR2B (0.51) | HRH2HTR5AHTR2BHTR2CADORA3 | |
| SCHEMBL14263512 | 0.80 | HRH2 (0.49) | HRH2HTR5AHTR2BHTR2CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747254-A1 | <SUP2/>? <SUB2/>?2B?5-HTSEROTONIN RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE THEREOF | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019529-A1 | 5-HT 2B SEROTONIN RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-23 | — | — | WO | disclosed |