Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.73 |
| ▸ | USP2 | O75604 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350666 | 0.95 | CYP2D6 (0.80) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL31350612 | 0.84 | MAOB (0.70) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL31350777 | 0.82 | MAOB (0.63) | CYP3A4CYP1A2CYP2D6USP2ALDH1A1 | |
| SCHEMBL31350899 | 0.81 | L3MBTL1 (0.71) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL15094226 | 0.81 | CYP3A4 (0.64) | CYP3A4KMT2AALDH1A1CYP3A5NAMPT | |
| SCHEMBL31350892 | 0.81 | MAOB (0.57) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL31350864 | 0.77 | CYP3A4 (0.61) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL31350821 | 0.77 | MAOB (0.56) | CYP3A4CYP1A2CYP2D6USP2MEN1 | |
| SCHEMBL31350825 | 0.77 | MAOB (0.56) | CYP3A4CYP1A2CYP2D6USP2TSHR | |
| SCHEMBL31351058 | 0.77 | MAOB (0.56) | CYP3A4CYP1A2CYP2D6USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084091-A1 | INHIBITORS OF SARS-COV-2 | TEXAS A & M UNIV SYS (US) | 2025-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084091-A1 | INHIBITORS OF SARS-COV-2 | ACE2, ACE, TMPRSS2 | CYP3A4 172/4885CYP1A2 379/4885CYP2D6 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.