Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 19/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.56 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128606 | 0.90 | ALDH1A1 (0.47) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3081916 | 0.89 | SSTR5 (0.62) | SSTR5KCNH2 | |
| SCHEMBL3137920 | 0.87 | ALDH1A1 (0.46) | SSTR5ALDH1A1 | |
| SCHEMBL3128617 | 0.87 | SSTR5 (0.47) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3137260 | 0.87 | USP2 (0.44) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3133924 | 0.87 | USP2 (0.44) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3133541 | 0.86 | SSTR5 (0.50) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3128281 | 0.85 | USP2 (0.47) | KCNH2ALDH1A1 | |
| SCHEMBL3134311 | 0.84 | SSTR5 (0.43) | SSTR5KCNH2ALDH1A1 | |
| SCHEMBL3128667 | 0.84 | SSTR5 (0.48) | SSTR5KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142528-B1 | 1-(1-BENZYLPIPERIDIN-4-YL)BENZIMIDAZ0LE -5-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS | HOFFMANN LA ROCHE (CH) | 2010-07-07 | — | — | EP | claimed |