Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | FHIT | P49789 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808110 | 0.83 | KDM4E (0.52) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL1628027 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL9271057 | 0.81 | KMT2A (0.51) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL17343185 | 0.76 | GAA (0.43) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL16684814 | 0.76 | ALDH1A1 (0.47) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL11809086 | 0.74 | KDM4E (0.46) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL13554532 | 0.74 | CYP3A4 (0.63) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL3191583 | 0.73 | SMN1; SMN2 (0.61) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL11853743 | 0.73 | MAPK1 (0.54) | GAAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL24772939 | 0.73 | GAA (0.53) | GAAALDH1A1SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |