Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.94 |
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL4081852 | 1.00 | ALDH1A1 (0.94) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL4081857 | 1.00 | ALDH1A1 (0.94) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL1330714 | 0.97 | — | — | |
| Nitrobenzene SCHEMBL2358164 | 0.97 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL1330825 | 0.97 | — | — | |
| Nitrobenzene SCHEMBL15525745 | 0.97 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL20411 | 0.97 | — | — | |
| Nitrobenzene SCHEMBL9669095 | 0.97 | — | — | |
| Nitrobenzene SCHEMBL2255264 | 0.97 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL25293390 | 0.94 | ALDH1A1 (0.94) | ALDH1A1LMNATSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605303-A | Synthesis method of delavirdine and intermediate thereof | 武汉工程大学 | 2022-06-10 | — | — | CN | claimed |
| CN-106622244-B | A kind of method nitrogen-doped carbon material package Co catalysts and prepare secondary-amine compound using it | 中南民族大学 | 2019-06-14 | — | — | CN | claimed |
| CN-108752463-A | A kind of preparation method and its usage of 2,4,4 '-tribromo Biphenyl Ether immunogene | 上海交通大学 | 2018-11-06 | — | — | CN | claimed |
| CN-108610225-A | A kind of method that transition metal-catalyzed nitro-aromatic prepares fragrant alkynes with terminal aryl group alkynes cross-coupling | 湖南科技大学 | 2018-10-02 | — | — | CN | claimed |
| CN-107406385-A | Process for producing diamine compound and intermediate thereof | 日产化学工业株式会社 | 2017-11-28 | — | — | CN | claimed |
| CN-104861138-B | A kind of polyurethane containing trianilino group and its preparation method and application | 黑龙江大学 | 2017-10-10 | — | — | CN | claimed |
| CN-105175716-B | A kind of preparation method of the polyamide film containing trianilino group | 黑龙江大学 | 2017-05-31 | — | — | CN | claimed |
| CN-104844813-B | A kind of preparation method of the polyamide film with electrochromic property | 黑龙江大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106622244-A | Nitrogen-doped carbon material encapsulated cobalt catalyst and method of using the catalyst to prepare secondary amine compounds | 中南民族大学 | 2017-05-10 | — | — | CN | claimed |
| CN-116528845-A | Novel aminoaromatic compound or pharmaceutically acceptable salt of the compound, and pharmaceutical composition for preventing or treating neurodegenerative disease comprising the same as active ingredient | 基础科学研究院 | 2023-08-01 | — | — | CN | disclosed |
| CN-110710533-B | Plant growth regulator composition containing flumetralin and prohexadione calcium | 江苏龙灯化学有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-110408233-B | P-sulfophenoxy cyanine dye and preparation method and application thereof | 北京大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-110710531-A | Method for increasing cotton yield and/or improving fiber quality | 江苏龙灯化学有限公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-110710533-A | Plant growth regulator composition containing flumetralin and prohexadione calcium | 江苏龙灯化学有限公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-101274898-A | Process for 4- amino-3-fluorophenol | UNIV SHANDONG WEIHAI (CN) | 2008-10-01 | — | — | CN | disclosed |
| WO-2006125208-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | WAYNE STATE UNIVERSITY (US) | 2006-11-23 | — | — | WO | disclosed |
| US-7101890-B2 | Benzazepine derivatives, drugs containing these and use of the same for producing drugs | SANOCHEMIA LTD. (MT) | 2006-09-05 | — | — | US | disclosed |
| US-20040067974-A1 | New benzazepine derivatives, drugs containing these and use of the same for producing drugs | SANOCHEMIA LTD. (MT) | 2004-04-08 | — | — | US | disclosed |
| US-6638925-B2 | In particular benzofuro(3a,3,2,ef)(2)benzazepin; treatment of Alzheimer's disease and related dementia conditions, Langdon-Down syndrome | SANOCHEMIA LTD. (MT) | 2003-10-28 | — | — | US | disclosed |
| US-20030092700-A1 | BENZAZEPINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME AND THEIR USE TO PREPARE MEDICAMENTS | SANOCHEMIA LTD. (MT) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092700-A1 | BENZAZEPINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME AND THEIR USE TO PREPARE MEDICAMENTS | PSEN2, BACE2, BACE1 | ALDH1A1 2241/4885LMNA 270/4885TSHR 4824/4885 |
| US-20040067974-A1 | New benzazepine derivatives, drugs containing these and use of the same for producing drugs | BACE2, PSEN2, BACE1 | ALDH1A1 1803/4885LMNA 386/4885TSHR 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.