Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 15/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957541 | 1.00 | KMT2A (0.46) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL30050019 | 0.84 | KMT2A (0.49) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL1191996 | 0.84 | KMT2A (0.46) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL29197376 | 0.84 | KMT2A (0.49) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL31351943 | 0.82 | ERBB2 (0.47) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL24569429 | 0.81 | ERBB2 (0.53) | GAAERBB2EGFRMAPT | |
| SCHEMBL29887863 | 0.81 | ERBB2 (0.53) | GAAERBB2EGFRMAPT | |
| SCHEMBL31351988 | 0.81 | ERBB2 (0.45) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL23750191 | 0.80 | ERBB2 (0.46) | KMT2AHPGDGAAERBB2EGFR | |
| SCHEMBL24570249 | 0.79 | L3MBTL1 (0.46) | KMT2AHPGDGAAERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025202889-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2025-10-02 | — | — | WO | disclosed |
| WO-2025051148-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技股份有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119320383-A | Nitrogen-containing heteroaryl compound, and preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-01-17 | — | — | CN | disclosed |