Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750376 | 1.00 | KMT2A (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL1191996 | 0.86 | KMT2A (0.46) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL29888756 | 0.85 | KMT2A (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL23750358 | 0.85 | KMT2A (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL31476147 | 0.85 | MAPT (0.49) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL23750359 | 0.85 | KMT2A (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL23750375 | 0.85 | MAPT (0.49) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL23750362 | 0.84 | KMT2A (0.45) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL24569506 | 0.82 | FGFR1 (0.54) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 | |
| SCHEMBL30050677 | 0.82 | GRM5 (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051148-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技股份有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119320383-A | Nitrogen-containing heteroaryl compound, and preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-01-17 | — | — | CN | disclosed |