Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750375 | 1.00 | MAPT (0.49) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1191996 | 0.86 | KMT2A (0.46) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31351997 | 0.85 | KMT2A (0.43) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23750359 | 0.85 | KMT2A (0.43) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29888756 | 0.85 | KMT2A (0.43) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23750376 | 0.85 | KMT2A (0.43) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23750358 | 0.85 | KMT2A (0.43) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL24569506 | 0.82 | FGFR1 (0.54) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23750374 | 0.81 | KMT2A (0.41) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31257582 | 0.80 | KMT2A (0.44) | MAPTFGFR1ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | COGENT BIOSCIENCES, INC. | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | ERBB2, ERBB3, EGFR | MAPT 72/4885FGFR1 18/4885ALDH1A1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.