SCHEMBL3135210

SCHEMBL3135210

COC(=O)C=C(C)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9483378 1.00
SCHEMBL4424904 1.00
SCHEMBL13751256 0.84 HCAR2 (0.48)
SCHEMBL4434083 0.80
SCHEMBL9654807 0.80
SCHEMBL9912439 0.80
SCHEMBL756884 0.80
SCHEMBL13224195 0.80 HCAR2 (0.43)
SCHEMBL3136549 0.80
SCHEMBL19968923 0.79 NPSR1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2024-04-30 US disclosed
US-20200354319-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME UNIV CORNELL (US) 2020-11-12 US disclosed
US-20140194383-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2014-07-10 US disclosed
EP-2694707-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME Cornell University (US) 2014-02-12 EP disclosed
WO-2013058824-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2013-04-25 WO disclosed
EP-1697388-B1 METHOD FOR PRODUCING PHOSPHONIUM SALTS BASF SE (DE) 2010-07-21 EP disclosed
US-7547807-B2 Method for producing phosphonium salts BASF SE (DE) 2009-06-16 US disclosed
US-20070123726-A1 Method for producing phosphonium salts BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) 2007-05-31 US disclosed
EP-1697388-A1 METHOD FOR PRODUCING PHOSPHONIUM SALTS BASF AKTIENGESELLSCHAFT (DE) 2006-09-06 EP disclosed
WO-2005058924-A1 METHOD FOR PRODUCING PHOSPHONIUM SALTS BASF AKTIENGESELLSCHAFT (DE) 2005-06-30 WO disclosed
US-4937308-A Preparation of alkyl O,O-dialkyl-γ-phosphonotiglates BASF AKTIENGESELLSCHAFT (DE) 1990-06-26 US disclosed
US-4661617-A PESTICIDES SANDOZ LTD. (CH) 1987-04-28 US disclosed
US-4511720-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1985-04-16 US disclosed
US-4355033-A TREATMENT OF HYPERTENSION HOFFMAN-LA ROCHE INC. (US) 1982-10-19 US disclosed
US-4244957-A HYPOTENSIVE AGENTS HOFFMAN-LA ROCHE INC. (US) 1981-01-13 US disclosed
US-4097496-A ANTIPROSTAGLANDIN ACTIVITY HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-27 US disclosed
US-4083990-A ANTIPROSTAGLANDIN EFFECT HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4078081-A Cyclopentane derivatives manufacture HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed
US-3984459-A ANTI-PROSTAGLANDINS HOECHST AKTIENGESELLSCHAFT (DT) 1976-10-05 US disclosed
US-3984455-A Prostaglandin E1 analogs THE UPJOHN COMPANY (US) 1976-10-05 US disclosed