⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434083 | 1.00 | — | — | |
| SCHEMBL13751256 | 0.84 | HCAR2 (0.48) | — | |
| SCHEMBL29053147 | 0.81 | HCAR2 (0.40) | — | |
| SCHEMBL1194992 | 0.81 | HCAR2 (0.40) | — | |
| SCHEMBL1194995 | 0.81 | HCAR2 (0.40) | — | |
| SCHEMBL9912439 | 0.80 | — | — | |
| SCHEMBL9483378 | 0.80 | — | — | |
| SCHEMBL3135210 | 0.80 | — | — | |
| SCHEMBL9654807 | 0.80 | — | — | |
| SCHEMBL4424904 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473295-B2 | Substituted straight chain spiro derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2025-11-18 | — | — | US | disclosed |
| CN-118344372-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255773-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118255774-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| EP-4077312-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| CN-114867721-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |
| WO-2021121327-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| CN-103958526-B | Pyrimidinediamine derivative, preparation method and medical application thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD. (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103958526-A | Pyrimidinediamine derivative, preparation method and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2014-07-30 | — | — | CN | disclosed |
| EP-1697388-B1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF SE (DE) | 2010-07-21 | — | — | EP | disclosed |
| US-7547807-B2 | Method for producing phosphonium salts | BASF SE (DE) | 2009-06-16 | — | — | US | disclosed |
| US-20070123726-A1 | Method for producing phosphonium salts | BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1697388-A1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058924-A1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-30 | — | — | WO | disclosed |
| EP-1449835-A2 | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | PHARMACIA & UPJOHN COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6043248-A | VIRICIDES FOR TREATING AN INDIVIDUAL INFECTED WITH THE HUMAN IMMUNODEFICIENCY VIRUS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035678-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |