Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352143 | 0.89 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL31352251 | 0.76 | MAPK14 (0.36) | MAPK14 | |
| SCHEMBL31352137 | 0.72 | POLB (0.36) | MAPK14 | |
| SCHEMBL31352257 | 0.72 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL31104648 | 0.66 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL31352388 | 0.66 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL23212908 | 0.62 | CYP1A2 (0.41) | RECQL | |
| SCHEMBL2292937 | 0.62 | CYP1A2 (0.41) | RECQL | |
| SCHEMBL28820045 | 0.62 | CYP1A2 (0.41) | RECQL | |
| SCHEMBL5848950 | 0.60 | ESR1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |