Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208170 | 0.83 | MEN1 (0.38) | MAPK14 | |
| SCHEMBL31352251 | 0.74 | MAPK14 (0.36) | MAPK14 | |
| SCHEMBL31352137 | 0.73 | POLB (0.36) | MAPK14 | |
| SCHEMBL31352124 | 0.72 | RECQL (0.38) | MAPK14 | |
| SCHEMBL31352143 | 0.70 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL31352388 | 0.67 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL31104648 | 0.67 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL29208147 | 0.67 | MEN1 (0.38) | MAPK14 | |
| SCHEMBL181965 | 0.62 | ALDH1A1 (0.55) | — | |
| SCHEMBL18130849 | 0.61 | MPO (0.40) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |