Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.50 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20306358 | 0.83 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL6610807 | 0.80 | DRD3 (0.57) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL9610941 | 0.77 | DRD3 (0.58) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL22792160 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL16050082 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL6612386 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL29535086 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL23587071 | 0.74 | DRD3 (0.55) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL3793301 | 0.74 | DRD3 (0.51) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL1290838 | 0.74 | DRD3 (0.51) | DRD3DRD4EPHB3DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |