Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.54 |
| ▸ | DRD4 | P21917 | 7/20 | 0.54 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352247 | 0.83 | DRD3 (0.50) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL9610941 | 0.80 | DRD3 (0.58) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL6610807 | 0.80 | DRD3 (0.57) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL23587071 | 0.77 | DRD3 (0.55) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL20798954 | 0.77 | DRD4 (0.35) | DRD3DRD4EPHB3MEN1KMT2A | |
| SCHEMBL19431253 | 0.77 | DRD4 (0.43) | DRD3DRD4EPHB3DRD2NPC1 | |
| SCHEMBL22792160 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL16050082 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL6612386 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A | |
| SCHEMBL29535086 | 0.77 | DRD3 (0.54) | DRD3DRD4EPHB3DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
| US-10005774-B2 | Syk inhibitors | GILEAD SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | DRD3 1018/4885DRD4 1861/4885EPHB3 3524/4885 |
| US-11820766-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | DRD3 1018/4885DRD4 1861/4885EPHB3 3524/4885 |
| US-10005774-B2 | Syk inhibitors | SYK, BTK, LYN | DRD3 3127/4885DRD4 4192/4885EPHB3 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.