SCHEMBL31352292

SCHEMBL31352292

COC(C)(C)Cn1cc(C(=O)O)cn1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
HSD17B10 Q99714 1/20 0.40
ACHE P22303 2/20 0.39
PLA2G4A P47712 1/20 0.39
HPGDS O60760 1/20 0.38
ALKBH2 Q6NS38 1/20 0.38
ALKBH1 Q13686 3/20 0.38
EGLN1 Q9GZT9 3/20 0.37
TTK P33981 1/20 0.36
XDH P47989 1/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31352164 0.86 L3MBTL1 (0.40) L3MBTL1ACHETTK
SCHEMBL31352316 0.82 CYP2C19 (0.42) L3MBTL1ACHE
SCHEMBL882433 0.82 L3MBTL1 (0.60) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS
SCHEMBL370482 0.77 L3MBTL1 (0.62) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS
SCHEMBL2148413 0.77 L3MBTL1 (0.57) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS
SCHEMBL17076856 0.77 MEN1 (0.43) L3MBTL1
SCHEMBL6919122 0.75 KIT (0.35)
SCHEMBL553834 0.74 L3MBTL1 (0.73) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS
SCHEMBL2828291 0.74 L3MBTL1 (0.68) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS
SCHEMBL27806606 0.74 L3MBTL1 (0.54) L3MBTL1HSD17B10ACHEPLA2G4AHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737449-A1 P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2026-05-06 EP disclosed
WO-2025002177-A1 P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF 长春金赛药业有限责任公司 2025-01-02 WO disclosed