Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 8/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590933 | 1.00 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30590936 | 0.90 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28983490 | 0.89 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL26111136 | 0.88 | EGFR (0.42) | ERBB2EPHB4EGFRRIPK2RET | |
| SCHEMBL24714039 | 0.84 | ENPP1 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29834791 | 0.84 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30822064 | 0.84 | ENPP1 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29834734 | 0.84 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL665187 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL2453138 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325471-A | EGFR inhibitors | 缆图药品公司 | 2025-01-17 | — | — | CN | disclosed |