Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31353046 | 0.80 | MAPK1 (0.41) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL26629110 | 0.76 | MAPK1 (0.61) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL20856579 | 0.76 | MAPK1 (0.56) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL4969468 | 0.73 | HSP90AA1 (0.49) | MAPK1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL25424796 | 0.72 | PDE7A (0.43) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL30214885 | 0.72 | TSHR (0.41) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL25236052 | 0.72 | TTR (0.46) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL29276121 | 0.72 | TSHR (0.41) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11800281 | 0.69 | TSHR (0.62) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL31353073 | 0.69 | TAAR1 (0.37) | TSHRALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143752-A | Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |