Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 13/20 | 0.67 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.57 |
| ▸ | TUBB | P07437 | 6/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355246 | 0.89 | GAA (0.83) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355268 | 0.84 | GAA (0.84) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355316 | 0.83 | GAA (0.74) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355328 | 0.81 | TUBB4A (0.83) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355257 | 0.81 | GAA (0.63) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355380 | 0.80 | GAA (0.88) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14022528 | 0.80 | GAA (1.00) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355365 | 0.79 | GAA (0.84) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14022527 | 0.78 | GAA (1.00) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31355350 | 0.77 | GAA (0.67) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250032485-A1 | APPLICATION OF IMIDAZO [1,2-A] PYRAZINE COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS IN THE PREPARATION OF ANTI-CORONAVIRUS DRUGS | UNIV GUANGZHOU MEDICAL (CN) | 2025-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032485-A1 | APPLICATION OF IMIDAZO [1,2-A] PYRAZINE COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS IN THE PREPARATION OF ANTI-CORONAVIRUS DRUGS | TOP1, TDP1, TOP2A | GAA 2008/4885MAPT 2846/4885KDM4E 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.