Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 6/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356240 | 0.92 | BCL2 (0.44) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31356004 | 0.92 | BCL2 (0.44) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31356234 | 0.92 | BCL2 (0.44) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31355761 | 0.90 | BCL2 (0.43) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31356102 | 0.90 | BCL2 (0.43) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31485142 | 0.88 | PIK3CA (0.55) | PIK3CABCL2MCL1ALDH1A1KMT2A | |
| SCHEMBL31355877 | 0.87 | PIK3CA (0.41) | STAT3PIK3CABCL2MCL1CRBN | |
| SCHEMBL31356056 | 0.83 | DDB1 (0.44) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31355888 | 0.82 | DDB1 (0.47) | STAT3BCL2MCL1CRBNDDB1 | |
| SCHEMBL31356126 | 0.81 | CRBN (0.43) | STAT3BCL2MCL1CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768392-A | Aryl or heteroaryl substituted glutarimide derivatives and uses thereof | 标新生物医药科技(上海)有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |