SCHEMBL31485142

SCHEMBL31485142

O=C1CCC(N2C(=O)c3cccc4c(NC(=O)CCCCCCCN5CCOCC5)ccc2c34)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 6/20 0.55
HDAC3 O15379 5/20 0.49
HDAC1 Q13547 5/20 0.49
NCOR2 Q9Y618 4/20 0.49
HDAC11 Q96DB2 3/20 0.49
HDAC2 Q92769 4/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
PTK2 Q05397 5/20 0.43
TERT O14746 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355952 0.92 PIK3CA (0.48) PIK3CAHDAC3HDAC1NCOR2HDAC11
SCHEMBL31355860 0.90 PIK3CA (0.48) PIK3CAHDAC3HDAC1NCOR2HDAC2
SCHEMBL31485123 0.90 PIK3CA (0.48) PIK3CAHDAC3HDAC1NCOR2HDAC2
SCHEMBL31355772 0.88 STAT3 (0.44) PIK3CAHDAC3HDAC1NCOR2HDAC2
SCHEMBL31484986 0.85 PARP1 (0.46) PIK3CAHDAC3HDAC1NCOR2HDAC2
SCHEMBL24329227 0.83 DDB1 (0.44) PIK3CAALDH1A1BCL2MCL1
SCHEMBL31355994 0.83 ALDH1A1 (0.48) HDAC3HDAC1NCOR2HDAC2HDAC6
SCHEMBL31485112 0.83 PARP1 (0.46) PIK3CAHDAC3HDAC1NCOR2HDAC2
SCHEMBL31485056 0.82 HDAC1 (0.47) HDAC3HDAC1NCOR2HDAC2HDAC6
SCHEMBL31355877 0.81 PIK3CA (0.41) PIK3CAALDH1A1KMT2ABCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 CN claimed